Monday, October 3, 2016

Arboviruses and Certain Other Viruses Assigned to Biosafety Level 3 BSL-3

Arboviruses and Certain Other Viruses Assigned to Biosafety Level 3 BSL-3


 Arboviruses and Certain Other Viruses Assigned to BSL-3
Aino Murray Valley enc.
Akabanec Nairobi sheep diseasea,i
Bannaa,f Ndumu
Bhanja Negishi
Central Eur. TBE b,d (Absettarov, Hanzalova, Hypr, and Kumlinge) Oropouchec
Orungo
Chikungunyac,d Peaton
Cocal Piryi
Dhori Powassan
Dobrava-Belgrade Puumala
Dugbe Rift Valley fevera,c,d,h,i
Evergladesc,d Rocioc
Flexal Sagiyama
Germistonc Sal Vieja
Getah San Perlita
Hantaanh Semliki Forest
Israel Turkey mening. Seoul
Japanese enc.h Sin Nombre
Juninc,d,h Spondweni
Kairi St. Louis enc.
Kimberley Thogoto
Koutango Turuna
Kumlinge (Cent. Eur. TBE) Venezuelan equine encephalitisc,d,h,i
Louping IIIa,c,h Vesicular stomatitus (Alagoas)h,i
Mayaro Wesselsbrona,c,i
Middelburg West Nile
Mobala Yellow feverc,d
Mopeiae Zingag
Mucamboc,d  
  1. The importation, possession, or use of this agent is restricted by USDA regulation or administrative policy.

  2. Central European Tick Borne Encephalitis virus (CETBE) is not a registered name in The International Catalogue of Arboviruses-1985. Until the registration issue has been resolved taxonomically, CETBE refers to the following group of very closely related, if not essentially identical, tick-borne flaviviruses isolated from Czechoslovakia, Finland and Russia: Absettarov, Hanzalova, Hypr, and Kumlinge. These four viruses are antigenically homogeneous and are distinguishable from Russian Spring-Summer encephalitis (RSSE) virus. While there is a vaccine available which confers immunity to the CETBE group of genetically (>98%) homogeneous viruses, the efficacy of this vaccine against RSSE virus infections has not been established. Thus, SALS has reclassified the CETBE group of viruses as Biosafety Level 3 when personnel are immunized with CETBE vaccine. RSSE remains classified as a Biosafety Level 4 virus.

  3. Subcommittee on Arbovirus Laboratory Safety (SALS) recommends that work with this agent should be conducted only in Biosafety Level 3 facilities that provide for HEPA filtration of all exhaust air prior to discharge from the laboratory.

  4. A vaccine is available and is recommended for all persons working with this agent.

  5. This virus is presently being registered in the Catalogue of Arboviruses.

  6. Scientists from the People's Republic of China have verbally reported Banna virus to be associated with severe human cases of encephalitis. Translations of the original publications from Chinese into English were not available for this revision.

  7. Zinga virus is now recognized as being identical to Rift Valley Fever virus.

  8. Export permit required from Department of Commerce.

  9. An importation or domestic transfer permit for this agent can be obtained from USDA/APHIS/VS.

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